Top Xx On The Bmj
Tuesday, November 7, 2017
Here is i of my favorites:
Seeing what you lot desire to encounter inwards randomised controlled trials: versions in addition to perversions of UKPDS data
Randomised controlled trials are objective, complimentary of bias, in addition to arrive at robust conclusions close the benefits in addition to risks of treatment, in addition to clinicians should last trained to rely on them; in addition to therefore says the gospel of testify based practice. In this article nosotros argue, using the United Kingdom prospective diabetes written report (UKPDS) equally an example, that at that topographic point is i phase inwards the bear of a randomised controlled trial—the interpretation in addition to dissemination of results—that is opened upwards to several biases that tin seriously distort the conclusions. By bias, nosotros hateful the epidemiological definition: anything that systematically distorts the comparisons betwixt groups. We volition debate that for certain biases arise when dissimilar stakeholders assign their private values to the interpretation of the in conclusion results of randomised controlled trials.